Homocysteine Induced Cerebrovascular Dysfunction: A Link to Alzheimer’s Disease Etiology

A high serum level of homocysteine, known as hyperhomocystenemia (HHcy) is associated with vascular dysfunction such as altered angiogenesis and increased membrane permeability. Epidemiological studies have found associations between HHcy and Alzheimer’s disease (AD) progression that eventually leads to vascular dementia (VaD).  VaD is the second most common cause of dementia in people older than 65, the first being AD. VaD affects the quality...

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Gauging Regional Differences in the HIV Prevalence Rate Among Injection Drug Users in the U.S.

This article aims to introduce and demonstrate the application of the standardization and decomposition analysis (SDA) method to gauge differences in HIV prevalence rates among injection drug users (IDUs) across regions (Northeast, South, Midwest, and West) in the U.S.  Using the SDA, the regional HIV prevalence rates were standardized and a rate difference between regions was decomposed into component effects, such as the “real” rate difference,...

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A Facile Method for Simultaneously Measuring Neuronal Cell Viability and Neurite Outgrowth

Neurite outgrowth is an important morphological phenotype of neuronal cells that correlates with their function and cell health, yet there are limited methods available for measuring this phenomenon. Current approaches to measuring neurite outgrowth are laborious and time-consuming, relying largely upon immunocytochemical staining of neuronal markers (e.g., beta-III tubulin or MAP2) followed by manual or automated microscopy for image acquisition...

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Study on High-Temperature Glass Lens Molding Process Using FEM Simulation

The glass molding process (GMP) can press glass perform into a shape of finished lens under high pressure and temperature conditions, and it is easy to achieve mass production. So, it has emerged as a promising alternative way to produce complex shapes lens. It is well known that viscoelastic is one important properties of glass at high temperature. In this study, A 4-pair generalized maxwell model was used to express viscoelastic of glass, and model...

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Prospective and Retrospective Memory Deficits Associated with Androgenic Anabolic Steroid Use

The recreational use of androgenic anabolic steroids (AAS) has been associated with a range of health and psychological problems in the past, but very little research has considered what impact AAS might have upon cognition and memory. The present study aimed to identify whether the recreational use of AAS is linked to deficits in everyday retrospective memory (RM) and everyday prospective memory (PM). We assessed self-reports of RM and PM in 25...

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